Health Encyclopedia

Search the Health Encyclopedia

Histoplasma skin test

Definition

The histoplasma skin test is used to check if you have been exposed to a fungus called Histoplasma capsulatum. The fungus causes an infection called histoplasmosis.

Alternative Names

Histoplasmosis skin test

How the Test is Performed

Your health care provider cleans an area of your skin, usually the forearm. An allergen is injected just below the cleaned skin surface. An allergen is a substance that causes an allergic reaction. The injection site is checked at 24 hours and at 48 hours for signs of a reaction. Occasionally, the reaction may not appear until the fourth day.

How to Prepare for the Test

No special preparation is necessary for this test.

How the Test will Feel

You may feel a brief sting as the needle is inserted just below the skin.

Why the Test is Performed

This test is used to determine if you have been exposed to the fungus that causes histoplasmosis.

Normal Results

No reaction (inflammation) at the site of the test is normal. The skin test can rarely make histoplasmosis antibody tests turn positive.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

A reaction means you have been exposed to Histoplasma capsulatum. It does not mean you have an active infection.

Risks

There is a slight risk of anaphylactic shock (a severe reaction).

Considerations

This test is rarely used today. It has been replaced by a variety of blood and urine tests.

References

Deepe GS. Histoplasma capsulatum (histoplasmosis). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 263.

Iwen PC, Thompson GR, Wiederhold NP. Mycotic diseases. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 60.

Review Date:8/26/2023
Reviewed By:Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

adam.com

The Agency for Health Care Administration (Agency) and this website do not claim the information on, or referred to by, this site is error free. This site may include links to websites of other government agencies or private groups. Our Agency and this website do not control such sites and are not responsible for their content. Reference to or links to any other group, product, service, or information does not mean our Agency or this website approves of that group, product, service, or information.

Additionally, while health information provided through this website may be a valuable resource for the public, it is not designed to offer medical advice. Talk with your doctor about medical care questions you may have.

Health Outcome Data

No data available for this condition/procedure.

Read More

Health Encyclopedia

More Features